The Properdin System: Composition and Function
نویسندگان
چکیده
منابع مشابه
The Properdin System and Immunity
High molecular weight polysaccharide complexes derived from normal and neoplastic mammalian tissues were found to combine with properdin and to inactivate C'3 in vitro. These polysaccharide preparations were also found to alter properdin levels and non-specific resistance to Gram-negative infection in mice. In these manifestations, the tissue polysaccharides bore a marked resemblance to bacteri...
متن کاملTHE PROPERDIN SYSTEM AND IMMUNITY V. THE BACTERICIDAL ACTIVI~ O~ Tm~ PROPERDIN SYSTEM BY ALASTAIR
Properdin, complement, and magnesium ions constitute the recognized components of the properdin system (1, 2). This system, which is present in the normal serum of man and other mammals, has the ability in vitro to lyse certain cells, destroy bacteria, and inactivate viruses, and appears to be involved in the resistance or susceptibility of experimental animals to infection, irradiation, and sh...
متن کاملAn Alternative Mechanism for the Properdin System
Evidence is presented that phenomena ascribed to the properdin system may be explained in terms of classical antibody (Ab) in combination with three of the components of complement (C'), i.e., C'(1), C'(4), and C'(2) respectively. The results suggest that the complex of properdin (P) with zymosan (Z) represents a mixture of Z.Ab, Z.Ab.C'(1, 4), Z.Ab-C'(1, 4, 2), and Z.Ab.C'(1, 4, 2) in a decaye...
متن کاملQuantitative Studies on the Properdin-complement System
The reaction of human, bovine, and pig properdin with excess zymosan exhibits an induction period followed by a rapidly accelerating formation of the properdin-zymosan (PZ) complex. Two methods for determining the quantity of PZ complex are given, one using human serum lacking properdin, the other using a fraction of pig serum containing complement components, C'1, C'3 and C'4.
متن کاملcompactifications and function spaces on weighted semigruops
chapter one is devoted to a moderate discussion on preliminaries, according to our requirements. chapter two which is based on our work in (24) is devoted introducting weighted semigroups (s, w), and studying some famous function spaces on them, especially the relations between go (s, w) and other function speces are invesigated. in fact this chapter is a complement to (32). one of the main fea...
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ژورنال
عنوان ژورنال: Vox Sanguinis
سال: 1978
ISSN: 0042-9007,1423-0410
DOI: 10.1111/j.1423-0410.1978.tb02893.x